Berlin Cures: Bc007
- BC 007 is a non-modified DNA aptamer that binds to and leads to the neutralization of autoantibodies that are directed against G-protein-coupled receptors (GPCR-AABs).
- Results of first successful treatment confirmed with two other Long COVID patients/
- Have shown positive results in the preclinical, clinical (phase I) as well as in the ongoing clinical phase IIa study in patients with advanced heart failure. – four compassionate use treatments with BC 007 were performed at the University of Erlangen in patients with Long Covid Syndrome (LCS) who also had autoantibodies of the same class. The neutralization of the autoantibodies caused an immediate easing of LCS. – The 59y male patient suffered from fatigue and other typical long covid symptoms. He was positive for different GPCR-autoantibodies. After a single treatment, the symptoms improved dramatically and the microcirculation, as measured in retinal angiography, also improved significantly.